Lymphocytes from patients with Wiskott-Aldrich syndrome (WAS) were studied 1) with prometaphase G banding to search for minor chromosome anomalies and 2) in mutagen stress assays to assess the extent of chromosome breakage under these conditions. One patient, a sporadic case of WAS, was found to hav
Skeletal abnormalities in Satoyoshi's syndrome: a radiographic study of eight cases
β Scribed by Shiro Ikegawa; Akira Nagano; Eijiro Satoyoshi
- Publisher
- Springer
- Year
- 1993
- Tongue
- English
- Weight
- 984 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0364-2348
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β¦ Synopsis
Skeletal abnormalities of eight patients with Satoyoshi's syndrome, a rare condition of unknown etiology characterized by progressive muscle spasms, alopecia, and diarrhea, were studied radiographically. Various skeletal changes were observed including metaphyseal lesions, slipping of multiple epiphyses, cystic lesions, acroosteolysis and osteolysis, bone fragmentation at tendinous insertions, fatigue fractures, and early osteoarthrosis. This wide range of lesions is likely to be due to repeated injuries to the growth plates, epiphyses, and tendon attachments in the growing skeleton caused by recurrent vigorous muscle spasms.
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