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Size of the directing moiety at carbon 5 of cytosine and the activity of human DNA(cytosine-5)methyltransferase

✍ Scribed by Thomas A. Hardy; David J. Baker; Edward M. Newman; Lawrence C. Sowers; Myron F. Goodman; Steven S. Smith

Book ID
115760741
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
593 KB
Volume
145
Category
Article
ISSN
0006-291X

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## Abstract We have developed a facile procedure for the purification of DNA methyltransferase activity from human placenta. The procedure avoids the isolation of nuclei and the dialysis and chromatography of large volumes. A purification of 38,000‐fold from the whole cell extract has been achieved