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Size of pancreas in children and adolescents with type I (insulin-dependent) diabetes

✍ Scribed by Altobelli, Emma; Blasetti, Annalisa; Verrotti, Alberto; Di Giandomenico, Vincenzo; Bonomo, Lorenzo; Chiarelli, Francesco

Publisher: John Wiley and Sons
Year: 1998
Tongue: English
Weight: 152 KB
Volume: 26
Category: Article
ISSN: 0091-2751
DOI: 10.1002/(sici)1097-0096(199810)26:8<391::aid-jcu3>3.0.co;2-d

No coin nor oath required. For personal study only.

✦ Synopsis

Purpose. The aim of this study was to evaluate the influence of insulin-dependent diabetes mellitus (IDDM) on the size of the pancreas in children.

Methods. Pancreas size was evaluated sonographically in a group of 60 diabetic children and adolescents, aged 3-15 years, and 60 sex-and age-matched healthy controls.

Results. A significant reduction in pancreatic area and other parameters was found in diabetic patients, particularly in children aged 8-12 and 13-15 years. The pancreas was larger in children 3-7 years old who had had IDDM for 2 years of less (mean size, 8.61 cm 2 ) than in children 8-12 and 13-15 years old who had had IDDM for more than 5 years (mean size, 8.06 and 8.40 cm 2 , respectively). An inverse correlation between area of the pancreas and duration of IDDM was seen in all age groups (p < 0.05).

Conclusions. Diabetes affects the growth of the pancreas in children with IDDM. Sonography can be used to noninvasively evaluate the influence of the disease on pancreas size.

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