Size Effect of Oxygen Anion on Partition Coefficients
β Scribed by MASUDA, AKIMASA
- Book ID
- 109642889
- Publisher
- Nature Publishing Group
- Year
- 1965
- Tongue
- English
- Weight
- 204 KB
- Volume
- 205
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/205971a0
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Precise partition coefficients in 1-octanol-water at 25 degrees C were determined for three 2-thiobarbituric acids and 14 barbituric acids with a wider range of substituents. The experimental log P values (log Pexp) of barbituric acids were correlated with the carbon number and the branching effect
A key parameter in membrane and chromatographic separations is the partition coefficient, the equilibrium ratio of the solute concentration in a porous or fibrous material to that in bulk solution. The theoretical effects of solute size on partition coefficients in straight pores or randomly oriente
## Abstract In this work, the possibility of the a priori predictive model COSMOβRS to describe partitioning of pharmaceutically active compounds in the octanolβwater system (__P__~OW~) in the presence of electrolytes is investigated. It is shown that the calculated values of __P__~OW~ depend on th
## Abstract Knowledge of partition coefficient (log __P__) data can play a critical role in understanding the pharmacokinetic and pharmacodistributive properties of toxic organophosphorus (OP) compounds. Using a recently published gas chromatographic method, the octanol:water log __P__ values for t