๐”– Bobbio Scriptorium
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Size and charge greatly affect the biodistribution of composite nanodevices in vivo

โœ Scribed by L.P. Balogh; M.S.T. Kariapper; B.M. Nair; W.G. Lesniak; S.S. Nigavekar; L.Yun Sung; M.K. Khan


Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
50 KB
Volume
2
Category
Article
ISSN
1549-9634

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Annamycin (Ann) is a non-cross-resistant lipophilic anthracycline antibiotic optimally suited for liposome delivery. We studied how vesicle size and presence of phospholipids with a high phase transition temperature and monosialoganglioside (GM I) in the liposome bilayers affect the pharmacokinetics