The aim of this study was to determine efficient parameters for an argon laser (spot diameter = 200 pm) to obtain and reproduce vessel anastomoses. It was performed in two groups of Wistar rats. In the first group (89 Laser impacts on 10 carotids), the fluence was continuously adjusted from 30 to 3,
Sixty argon laser-assisted anastomoses in rats: Macroscopic and histological studies
β Scribed by V. L. Martinot; V. A. Mitchell; S. R. Mordon; M. Schoofs; P. N. Pellerin; J. M. Brunetaud
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 521 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0738-1085
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β¦ Synopsis
The present in vivo study was undertaken to evaluate the patency rate and histological appearance of 30 venous anastomoses and 30 carotid anastomoses in Wistar rats using a laser. An argon laser was used with the following parameters: power, 100 mW; time, 3 seconds; continuous mode; spot, 200 pm (fluence, 950 J/cm2; irradiance, 320 W/cm2). The macroscopic appearance and patency rate were evaluated at different postoperative intervals (30 days and 60 days). In the venous group, the patency rate was 100% with no saccular pseudo-aneurysm. In the arterial group, the pa-tency rate was 93% with three saccular pseudo-aneurysms and two thromboses. Histological studies noted slight and transitory modifications of the media in the arterial group. In the venous group, the modifications appeared under the endothelium. Since the procedure was similar in both groups, the lack of pseudo-aneurysm formation in the venous group can be explained by a lower intravascular pressure.
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