Six novel tachykinin- and bombesin-related peptides from the skin of the Australian frog Pseudophryne güntheri
✍ Scribed by Maurizio Simmaco; Cinzia Severini; Daniela De Biase; Donatella Barra; Francesco Bossa; John D. Roberts; Pietro Melchiorri; Vittorio Erspamer
- Book ID
- 119142284
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 610 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0196-9781
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## Abstract Two novel antimicrobial peptides with similarity to brevinin‐2 family are purified and characterized from the skin secretions of the frog, __Rana nigrovittata__. Their amino acid sequences were determined as GAFGNFLKGVAKKAGLKILSIAQCKLSGTC (__brevinin‐2‐RN1__) and GAFGNFLKGVAKKAGLKILSIAQ
The secretion of the skin glands of the 'orange-thighed frog' Litoria xanthomera contains seven peptides. One of these is the know hypotensive peptide caerulein. Two new peptides, caerin 1.6 [GLFSVLGAVAKHVLPHVVPVIAEKL(NH2)], and caerin 1.7 [GLFKVLGSVAKHLLPHVAPVIAEKL(NH2)] show antibacterial properti