Six color flow cytometry detects plasma cells expressing aberrant immunophenotype in bone marrow of healthy donors

Sensitivity of combined DNA/immunophenot

Sensitivity of combined DNA/immunophenotype flow cytometry for the detection of low levels of aneuploid lymphoblastic leukemia cells in bone marrow

✍ Ralf Nowak; Uta Oelschlaegel; Ulrich Schuler; Heidrun Zengler; Rita Hofmann; Ger 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 145 KB 👁 2 views

By simultaneous DNA staining and immunophenotyping, the aneuploid blasts of acute lymphoblastic leukemia (ALL) can be quantitated by flow cytometry. The present study evaluates the application of this method for the detection of minimal residual disease (MRD). For this purpose leukemia cells with kn