<p>Focused on central nervous system (CNS) drug discovery efforts, this book educates drug researchers about the blood-brain barrier (BBB) so they can affect important improvements in one of the most significant β and most challenging β areas of drug discovery.</p><p>β’Β Written by world experts to pr
Sites of Drug Action in the Human Brain
β Scribed by Anat Biegon (Editor); Nora D. Volkow (Editor)
- Publisher
- CRC Press
- Year
- 1995
- Leaves
- 197
- Edition
- 1
- Category
- Library
No coin nor oath required. For personal study only.
β¦ Synopsis
Sites of Drug Action in the Human Brain uses the results of recent analyses of the regional brain distribution and binding pattern of drugs in the human brain. This new book specifically addresses drugs of abuse and treats the effects of various drugs on behavior and mood, as well as on metabolism and blood flow in the human brain. It also presents the methodological aspects of investigating the sites of drug action in the human brain.
Because it focuses on the living human brain, this book differs from other books on the subject, which primarily use the results of postmortem studies. Sites of Drug Action in the Human Brain therefore provides valuable information on the clinical aspects of drug intoxification, addiction, and toxicity.
β¦ Table of Contents
Chapter 1. Localization and Characterization of Drug Binding Sites in the Human Brain: Methodological Considerations, Chapter 2. Autoradiographic Localization of Benzodiazepine Receptor in the Human Brain Post-Mortem, Chapter 3. In Vivo Imaging of Benzodiazepine Receptors with Positron Emission Tomography, Chapter 4. Effects of Benzodiazepine on Behavior, Mood, and Regional Cerebral Metabolism, Chapter 5. Quantitative Autoradiography and Cannabinoid Receptors in the Human Brain Post-Mortem, Chapter 6. The Effects of Marihuana in the Human Brain Measured with Regional Brain Glucose Metabolism Nora D. Volkow, Hampton Gillespie, Lawrence Tancredi, and Leo Hollister, Chapter 7. Quantitative Autoradiographic Localization and Characterization of Cocaine Binding Sites in the Human Brain Post-Mortem, Chapter 8. PET Studies of Cocaine in Human Brain, Chapter 9. Autoradiographic Distribution of Multiple Opioid, Sigma, and Phencyclidine Receptor Binding Sites in the Human Brain, Chapter 10. Imaging Opiate Receptor In Vivo, Chapter 11. The Use of Positron Emission Tomography to Study the Acute Effects of Addictive Drugs on Cerebral Metabolis, Discussion, Index
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