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Site-specific recombinases in genetic engineering: Modern in vivo technologies

✍ Scribed by B. Ostash


Book ID
111495793
Publisher
Allerton Press Inc
Year
2010
Tongue
Ukrainian
Weight
197 KB
Volume
44
Category
Article
ISSN
0095-4527

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In Vivo Determination of Substrate Speci
✍ Sung Yun Kim; Kye Won Park; Yong Jae Lee; Sung Hoon Back; Jae Hwan Goo; Ohkmae K πŸ“‚ Article πŸ“… 2000 πŸ› Elsevier Science 🌐 English βš– 128 KB

Hepatitis C virus (HCV) NS3 protease is responsible for the processing of the viral polyprotein and is considered as a primary target for the development of anti-HCV therapy. We have developed a genetic method in yeast to screen for good substrate sequences of the NS3 protease. A library of fusion p