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Site-specific Protein Cross-Linking with Genetically Incorporated 3,4-Dihydroxy-L-Phenylalanine

✍ Scribed by Aiko Umeda; Gabrielle Nina Thibodeaux; Jie Zhu; YungAh Lee; Zhiwen Jonathan Zhang

Book ID
101820681
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
231 KB
Volume
10
Category
Article
ISSN
1439-4227

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✦ Synopsis

Abstract

Come together right now with L‐DOPA: Chemical cross‐linking is widely used to study protein–protein interactions. However, many cross‐linking agents suffer from low reactivity or selectivity. An efficient and selective reaction of site‐specific protein cross‐linking was achieved using genetically incorporated 3,4‐dihydroxy‐L‐phenylalanine.magnified image

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