Site-specific fluorescent probing of RNA molecules by unnatural base-pair transcription for local structural conformation analysis

New Approach for Local Structure Analysi

New Approach for Local Structure Analysis of the Tyrosine Domain in Proteins by Using a Site-Specific and Polarity-Sensitive Fluorescent Probe

✍ Suming Chen; Xiaohua Li; Huimin Ma 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 273 KB 👁 2 views

## Abstract **Designer label**: A newly developed polarity‐sensitive fluorescent probe (DBHA) was combined with a tyrosine‐specific labelling method that uses transition metal catalysis, and was successfully used in local structural analysis of the Tyr108 domain in Cu/Zn superoxide dismutase (SOD;