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Site-specific Dimensions Across a Highly Denatured Protein; A Single Molecule Study

✍ Scribed by Evan R. McCarney; James H. Werner; Summer L. Bernstein; Ingo Ruczinski; Dmitrii E. Makarov; Peter M. Goodwin; Kevin W. Plaxco


Book ID
116662333
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
369 KB
Volume
352
Category
Article
ISSN
0022-2836

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## Abstract The measurement of protein binding of highly hydrophobic molecules is challenging due to poor solubility and strong adsorption, and further complicated by the competition of lipophilic partition in biological systems. Here, an attempt is presented to simultaneously simulate protein bind