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Site-specific bidirectional efflux of 2,4-dinitrophenyl-S-glutathione, a substrate of multidrug resistance-associated proteins, in rat intestine and Caco-2 cells

✍ Scribed by Tomoharu Yokooji; Teruo Murakami; Ryoko Yumoto; Junya Nagai; Mikihisa Takano


Book ID
111710207
Publisher
Pharmaceutical Press
Year
2007
Tongue
English
Weight
543 KB
Volume
59
Category
Article
ISSN
2042-7158

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Do multidrug resistance-associated prote
✍ Young-Joo Lee; Hiroyuki Kusuhara; Yuichi Sugiyama πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 140 KB

The purpose of this study was to examine the role of multidrug resistanceassociated protein-1 and -2 (Mrp1 and Mrp2) in the efflux transport of organic anions across the blood-cerebrospinal fluid (CSF) barrier. The CSF concentration of estradiol-17b-glucuronide (E 2 17bG) and 2,4-dinitrophenyl-S-glu