Site-Selective Adhesion of Hydroxyapatite Microparticles on Charged Surfaces in a Supersaturated Solution

✍ Scribed by P.X. Zhu; Y. Masuda; K. Koumoto

• Publisher: Elsevier Science
• Year: 2001
• Tongue: English
• Weight: 496 KB
• Volume: 243
• Category: Article
• ISSN: 0021-9797
• DOI: 10.1006/jcis.2001.7888

✦ Synopsis

Site

-selective adhesion of hydroxyapatite (HAp) microparticles to NH 2 -terminated self-assembled monolayers (NH 2 -SAM, positive surface) and OH-SAM (negative) was investigated in the present paper. HAp microparticles were measured to be negatively charged, and homogeneously formed at 50 • C in the simulated body fluid (SBF) with high supersaturation degree (1.5 SBF; the concentrations of Ca 2+ and PO 3- 4 alone are 1.5 times that in 1.0 SBF) buffered carefully at 7.6 ∼ 7.7. The zeta potential of microparticles decreased from -11.5 mV to neutrality owing to the absorption of cations accompanied by the simultaneous growth of microparticles. The micropattern of HAp particulate films was successfully fabricated by the use of site-selective adhesion of HAp microparticles on the positive NH 2 -SAM owing to the attractive electrostatic interactions. The quantitative analysis using quartz crystal microbalance also confirmed the identical phenomena.