## Abstract In a series of 151 autopsies on cases of malignant disease, 12 (7.9 per cent) were found to have involvement of the diaphragm as compared with 5 (3.4 per cent) which had metastases in the spleen. Secondary deposits from the bronchus and stomach were rarely seen in comparison with those
Site preference of metastatic tumours of the brain
β Scribed by Graf, Anton-Helmut ;Buchberger, Wolfgang ;Langmayr, Hans ;Schmid, Kurt W.
- Publisher
- Springer-Verlag
- Year
- 1988
- Tongue
- English
- Weight
- 515 KB
- Volume
- 412
- Category
- Article
- ISSN
- 0174-7398
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## Abstract ## Background The neurotropic herpes simplex virus mutant HSV1716 lacks the gene encoding the virulence factor ICP34.5 and cannot replicate in nonβdividing cells where proliferating cell nuclear antigen (PCNA) is not actively engaged in cellular DNA synthesis. In the brain, tumoral exp