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Site-directed mutagenesis of the phosphorylation site of cofilin: Its role in cofilin-actin interaction and cytoplasmic localization

✍ Scribed by Nagaoka, Rie ;Abe, Hiroshi ;Obinata, Takashi

Publisher: John Wiley and Sons
Year: 1996
Tongue: English
Weight: 993 KB
Volume: 35
Category: Article
ISSN: 0886-1544
DOI: 10.1002/(sici)1097-0169(1996)35:3<200::aid-cm3>3.0.co;2-c

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✦ Synopsis

It has been demonstrated that the activity of ADF and cofilin, which constitute a functionally related protein family, is markedly altered by phosphorylation, and that the phosphorylation site is Ser 3 in their amino acid sequences [Agnew et al.,

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