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Site-directed mutagenesis of elongation factor Tu : The functional and structural role of residue Cys81

✍ Scribed by Pieter H. ANBORGH; Andrea PARMEGGIANI; Jiří JONÁK

Book ID
115129512
Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
728 KB
Volume
208
Category
Article
ISSN
1432-1327

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Effects of mutagenesis of residue 221 on
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✍ Senyene Eyo Hunter; Linda L Spremulli 📂 Article 📅 2004 🏛 Elsevier Science 🌐 English ⚖ 535 KB

During protein biosynthesis, elongation factor Tu (EF-Tu) delivers aminoacyl-tRNA (aa-tRNA) to the A-site of ribosomes. This factor is highly conserved throughout evolution. However, several key residues differ between bacterial and mammalian mitochondrial EF-Tu (EF-Tu mt ). One such residue is Ser2