Site-dependence of invasiveness of ECA109 human oesophageal carcinoma cells in nude mice

✍ Scribed by Gao Jin; Xue Kexue; Li Baogui; Dong Huayi; Wei Lisheng; Zhang Zhaohe; Tian Shen; Xu Zhengue

• Book ID: 104634784
• Publisher: Springer
• Year: 1984
• Tongue: English
• Weight: 632 KB
• Volume: 2
• Category: Article
• ISSN: 0262-0898
• DOI: 10.1007/bf00132927

✦ Synopsis

ECA109 human oesophageal carcinoma cells were injected either subcutaneously or intraperitoneally into BALB/CATc 1-nu/nu mice. After 23 weeks tumours were examined histologically and by scanning electron microscopy. Subcutaneous ECA109 tumours were well-delineated without signs of invasion. By contrast, intra-abdominal tumours invaded into the abdominal wall and abdominal organs. This result provides us with another example of site-dependence of invasion in vivo.