Sister chromatid exchanges induced in rabbit lymphocytes by ethylene oxide after inhalation exposure
β Scribed by Yager, Janice W. ;Benz, R. Daniel
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 1982
- Weight
- 978 KB
- Volume
- 4
- Category
- Article
- ISSN
- 0192-2521
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## Abstract Lymphocyte culture systems have the major advantage of permitting the analyssis of in vivo cytogenetic damage with minimal injury to the animal under study. This paper describes a rat lymphocyte culture system designed for the study of sister chromatid exchange (SCE) induced by in vivo
Structural, and numeric chromosome aberrations (CA), sisterchromatid exchange (SCE), phytohe magglutinin stimulation (ti), proliferative rate index (PRI), and UV light-induced unscheduled DNA-synthesis (UDS) were investigated in peripheral blood lymphocytes (PBL) of 48 historical controls ("Controls