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Sister chromatid exchanges induced by nitrogen mustard in Fanconi's anemia. Application to the detection of heterozygotes and interpretation of the results

✍ Scribed by Roland Berger; Alain Bernheim; Maryvonne Le Coniat; Danièle Vecchione; Gérard Schaison


Book ID
119102459
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
445 KB
Volume
2
Category
Article
ISSN
0165-4608

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The rate of sister chromatid exchanges p
✍ K. Hayashi; W. Schmid 📂 Article 📅 1975 🏛 Springer 🌐 English ⚖ 356 KB

The incidence of structural chromosome aberrations and the rate of sister chromatid exchanges (SCE) was investigated in lymphocyte cultures from a patient with typical Fanconi's anemia and his parents. The rate of SCEs was found to be normal. In experiments with the alkylating agent Trenimon the SCE