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Sister chromatid exchanges in balanced translocation carriers and in patients with unbalanced karyotypes

✍ Scribed by C. Stoll; D. S. Borgaonkar; P. Bigel

Publisher
Springer
Year
1977
Tongue
English
Weight
322 KB
Volume
37
Category
Article
ISSN
0340-6717

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✦ Synopsis

Sister chromatid exchanges (SCEs) were studied in peripheral human leukocytes from 16 patients with balanced translocations or with unbalanced karyotypes, and from 4 controls. No difference was seen between these two groups of people in the mean number of SCEs per cell, or in the total number of SCEs observed for each pair of autosomes involved in the translocations studied. With this last number no difference from the expected number of SCEs, if one supposes that SCEs follow a random distribution, was seen.

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