Sister chromatid exchange in regenerating liver and bone marrow cells of mice exposed to styrene
โ Scribed by Mary K. Conner; Yves Alarie; Rebecca L. Dombroske
- Book ID
- 116072461
- Publisher
- Elsevier Science
- Year
- 1979
- Tongue
- English
- Weight
- 198 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0041-008X
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Differential labeling of sister chromatids was achieved simultaneously in murine alveolar macrophages, regenerating liver, and bone marrow cells of partially hepatectomized mice as well as in alveolar macrophages and bone marrow cells of nonhepatectomized mice. The mean frequency of SCE/cell +/-S.D.
BrdU and BrdC have been employed as DNA labeling agents for differentiation of sister chromatids and for extension of sister chromatid exchange (SCE) methods to regenerating murine liver cells in vivo. Comparisons were made between bone marrow and liver cells isolated simultaneously from mice follow
In vivo sister chromatid exchange induced by 1,2-dichloroethane (DCE) was studied in bone marrow cells of mice after acute treatment for 24 hr. With the exception of the lowest concentration (0.5 mg/kg), each treated series exhibited a statistically significant increase in SCEs when compared with th