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SIRT1 negatively regulates HDAC1-dependent transcriptional repression by the RBP1 family of proteins

✍ Scribed by Binda, O; Nassif, C; Branton, P E

Book ID: 110072991
Publisher: Nature Publishing Group
Year: 2008
Tongue: English
Weight: 351 KB
Volume: 27
Category: Article
ISSN: 0950-9232
DOI: 10.1038/sj.onc.1211014

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## Abstract Rac1, a member of the Rho family GTPases, participates in a variety of cellular functions including lamellipodia formation, actin cytoskeleton organization, cell growth, apoptosis, and neuronal development. Recent studies have implicated Rac1 in cytoskeletal abnormalities, production of