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SIRT1 Gene Silencing: A Potential Therapeutic Strategy for Pancreatic Cancer

โœ Scribed by V. Dudeja; R. Chugh; H.M. Bezek; S.J. Skube; N. Mujumdar; Y. Yokoyama; D. Borja-Cacho; D. Rajinder; S.M. Vickers; A.K. Saluja

Book ID
116706049
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
216 KB
Volume
158
Category
Article
ISSN
0022-4804

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Sirtuin-3 (SIRT3), a novel potential the
Sirtuin-3 (SIRT3), a novel potential therapeutic target for oral cancer
โœ Turki Y. Alhazzazi; Pachiyappan Kamarajan; Nam Joo; Jing-Yi Huang; Eric Verdin; ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 455 KB

## BACKGROUND Several sirtuin family members (SIRT1-7), which are evolutionarily conserved NAD-dependent deacetylases, play an important role in carcinogenesis. However, their role in oral cancer has not yet been investigated. Therefore, the objective of this study was to investigate whether sirtui