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siRNA delivery using peptide transduction domains

✍ Scribed by Akiko Eguchi; Steven F. Dowdy


Book ID
116918885
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
234 KB
Volume
30
Category
Article
ISSN
0165-6147

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Due to their intracellular permeability, protein transduction domains (PTDs) have been widely used to deliver proteins and peptides to mammalian cells. However, their performance in gene delivery has been relatively poor. To improve the efficiency of PTD-mediated gene delivery, we synthesized a new