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Sinus histiocytosis mimicking metastatic melanoma in lymph nodes of a patient with a large joint prosthesis: Case report and review of the literature

✍ Scribed by Caleb K. Charny; Glenn Jacobowitz; Jonathan Melamed; Mona Tata; Matthew N. Harris

Publisher: John Wiley and Sons
Year: 1995
Tongue: English
Weight: 289 KB
Volume: 60
Category: Article
ISSN: 0022-4790
DOI: 10.1002/jso.2930600212

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✦ Synopsis

Malignant melanoma metastases to regional lymph nodes may be mimicked by several non-neoplastic processes, including sinus histiocytosis induced by fragments shed from joint prostheses. A patient who had an elective lymph node dissection for malignant melanoma and was found to have "post-prosthesis lymph node histiocytosis" resembling metastatic disease is described. Knowledge of the patient's past history of a total shoulder joint replacement along with the use of polarized light microscopy to identify birefringent particles of prosthetic debris allows for an accurate histologic diagnosis. o 1995

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