## Abstract A biodegradable composite scaffold was developed using β‐tricalcium phosphate (β‐TCP) with chitosan (CS) and gelatin (Gel) in the form of a hybrid polymer network (HPN) via co‐crosslinking with glutaraldehyde. Various types of scaffolds were prepared by freezing and lyophilizing. These
Sintering and robocasting of β-tricalcium phosphate scaffolds for orthopaedic applications
✍ Scribed by Pedro Miranda; Eduardo Saiz; Karol Gryn; Antoni P. Tomsia
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 777 KB
- Volume
- 2
- Category
- Article
- ISSN
- 1742-7061
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✦ Synopsis
beta-Tricalcium phosphate (beta-TCP) scaffolds with designed, three-dimensional (3-D) geometry and mesoscale porosity have been fabricated by direct-write assembly (robocasting) techniques. Concentrated beta-TCP inks with suitable viscoelastic properties were developed to enable the fabrication of the complex 3-D structures. A comprehensive study of the sintering behavior of TCP as a function of the calcium content in the starting powder was also carried out, and the optimal heat treatment for fabricating scaffolds with dense beta-TCP rods has been determined. Such analysis provides clues to controlling the microstructure of the fabricated structures and, therefore, enabling the fabrication by robocasting of TCP scaffolds with tailored performance for bone tissue engineering applications.
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