Singlet oxygen production from photodynamic sensitizers
β Scribed by C.S. Foote; D.C. Dobrowolski
- Publisher
- Elsevier Science
- Year
- 1984
- Weight
- 91 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0047-2670
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π SIMILAR VOLUMES
## Abstract Singlet oxygen (^1^O~2~) is the major cytotoxic agent responsible for cell killing for typeβII photodynamic therapy (PDT). An empirical fourβparameter macroscopic model is proposed to calculate the βapparent reacted ^1^O~2~ concentrationβ, [^1^O~2~]~__rx__~, as a clinical PDT dosimetry
Eosin, a known generator of singlet oxygen, applied to leaf discs of Pisum sativum L. sensitized the inhibition of photosynthesis. Analysis of partial photosynthetic electron-transport reactions and of the kinetics of variable chlorophyll fluorescence located the damage at photosystem II. This injur