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SINGLET OXYGEN INDUCED MUTAGENESIS OF BENZO[α]PYRENE DERIVATIVES

✍ Scribed by John L. Seed; Kathleen G. Specht; Thomas A. Dahl; W. Robert Midden

Book ID
114895630
Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
823 KB
Volume
50
Category
Article
ISSN
0031-8655

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Synthesis of 6-substituted benzo[a]pyren
Synthesis of 6-substituted benzo[a]pyrene-α-14C derivatives
✍ James L. Hicks; J. Richard Heys 📂 Article 📅 1981 🏛 John Wiley and Sons 🌐 French ⚖ 332 KB

## Abstract 6‐Lithiobenzo[__a__]pyrene was carbonated to produce benzo[__a__]pyrene‐6‐carboxylic‐^14^C acid, which was in turn used in the preparation of several derivatives. Methylation to the ester was followed by LiAlH~4~ reduction to 6‐hydroxymethyl‐^14^C‐benzo[__a__]pyrene. An efficient oxidat