𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Single-tablet determination of reserpine at the microgram level. Estimation of reserpine in the presence of protoveratrine a and other active drug components

✍ Scribed by William J. Weaver


Publisher
John Wiley and Sons
Year
1966
Tongue
English
Weight
278 KB
Volume
55
Category
Article
ISSN
0022-3549

No coin nor oath required. For personal study only.

✦ Synopsis


Mixtures of reserpine and other drugs can be resolved by thin-layer chromatography on silica gel, following extraction from single tablets with chloroform. Quantitation is accomplished by visual inspection, and is accurate to within 10 per cent.

H E PLTRPOSE of this investigation was to pro-Tvide a rapid , sensitive, reliable analytical procedure to measure tablet-to-tablet variation of the active ingrcdients in tablets containing reserpine, protoveratrine A, and hydroflumethiazide. Each tablet contains: l'rotoveratriue ' 2 . . .