We investigated the effects of temperature and pH on single strand-conformation polymorphism (SSCP) analyzed by capillary electrophoresis (CE) using short-chain linear polyacrylamide as the sieving medium. Nine different mutations (in factor V, cystathionine b-synthase, and methylenetetrahydrofolate
✦ LIBER ✦
Single-strand conformation polymorphism analysis by capillary zone electrophoresis in neutral pH buffer
✍ Scribed by Cecilia Gelfi; Agnese Viganó; Mario Curcio; Pier Giorgio Righetti; Sabina Carla Righetti; Elisabetta Corna; Franco Zunino
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 164 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0173-0835
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## Detection of mutations and polymorphisms in the p53 tumor suppressor gene by single-strand conformation polymorphism analysis Deciphering the genetic mechanisms in cancer development requires analysis of a large number of tumors for consistent genetic alterations. Single-strand conformational p