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Single-step allele-specific polymerase chain reaction HLA-DQ genotyping using ARMS primers

✍ Scribed by Picard, Jean K.


Book ID
123549624
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
578 KB
Volume
38
Category
Article
ISSN
0198-8859

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Single nucleotide polymorphisms (SNPs) are becoming widely recognized as the new currency for gene mapping as increasing numbers are discovered. Here we outline a method for their rapid analysis based on an allele-specific polymerase chain reaction (PCR) which employs a competitive approach, whereby