Single-sequence correlation chromatography A novel technique to decrease detection limits
β Scribed by D.J. Louwerse; H.F.M. Boelens; H.C. Smit
- Book ID
- 102981592
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- English
- Weight
- 864 KB
- Volume
- 256
- Category
- Article
- ISSN
- 0003-2670
No coin nor oath required. For personal study only.
β¦ Synopsis
A new method, bemg an mtermechate between smgle-mjectlon chromatography and conventIona correlation chromatography, LS described With respect to smgle-inJectIon chromatography, the mjection volume can be slgmficandy enlarged However, the rectangular Input function IS modulated with a fmestructure A deconvolutron procedure makes 11 possible to preserve a good peak resolution for the fast elutmg narrow peaks, while other more broadened peaks can be treated m a conventIonal way In both cases the signal-to-nmse ratlo IS Improved, and the detectIon hmlt 1s decreased
The theoretIca background IS presented, and the feasiblhty of the method 1s confumed by slmulatlon stuches and experiments Potentially, gradlent elutlon hqmd chromatography or programmed-temperature gas chromatography IS stdl apphcable, m contrast to conventIona correlation and multiplex techmques
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