Single photon emission computed tomography (SPECT) in probable Huntington's chorea (HC)
β Scribed by F. Leblhuber; B. Brucker; F. Reisecker; A. Trenkler; E. Deisenhammer
- Publisher
- Springer
- Year
- 1989
- Tongue
- English
- Weight
- 267 KB
- Volume
- 1
- Category
- Article
- ISSN
- 1435-1463
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We present two case studies, one of generalized chorea and one of hemichorea, both after severe hypoglycemia episodes. Both cases showed hyperperfusion in their SPECT scans. The MRI and SPECT findings serve as clues regarding the role of basal ganglion dysfunction associated with chorea.
## Abstract We compared perfusion of prefrontal, motor, and sensory cortices and basal ganglia in 29 Huntington's disease (HD) patients and nine controls. We found a significant reduction in perfusion in patients with HD of short (<6 years, n=10), medium (6β10 years, n=8), and long duration (>10 ye