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Single nucleotide polymorphisms ofABCB1(MDR1) gene and distinct haplotype profile in a West Black African population

โœ Scribed by Aurel C. Allabi; Yves Horsmans; Bouchra Issaoui; Jean-Luc Gala


Publisher
Springer
Year
2005
Tongue
English
Weight
324 KB
Volume
61
Category
Article
ISSN
0031-6970

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Interindividual variation in the expression of the carcinogen- and estrogen-metabolizing enzymes cytochrome P4501B1 and 1A1 (CYP1B1 and CYP1A1) has been detected in human lung. To search for polymorphisms with functional consequences for CYP1B1 and CYP1A1 gene expression, we examined 1.5 kb of the p