Investigating possible genetic polymorphisms and gene-environment interactions in the etiology of human conotruncal defects is a prudent research approach. In this study we explore gene-only and gene-environment effects of 32 single nucleotide polymorphisms (SNPs) on conotruncal defect risks. The ge
✦ LIBER ✦
Single-nucleotide polymorphisms of VEGF gene are associated with risk of congenital valvuloseptal heart defects
✍ Scribed by Ádám Vannay; Barna Vásárhelyi; Mária Környei; András Treszl; Gergely Kozma; Balázs Györffy; Tivadar Tulassay; Endre Sulyok
- Book ID
- 116190425
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 88 KB
- Volume
- 151
- Category
- Article
- ISSN
- 1097-6744
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## Abstract **INTRODUCTION:** Clark (1996) proposed that abnormal blood flow is related to some congenital cardiovascular malformations (CCVMs), particularly CCVM with obstruction to blood flow. Our hypothesis is that CCVMs may relate to genes that affect blood coagulation or flow. We studied wheth