Single nucleotide polymorphisms and mRNA expression of VEGF-A in papillary thyroid carcinoma: Potential markers for aggressive phenotypes

High prevalence of BRAF mutation in a Br

High prevalence of BRAF mutation in a Brazilian cohort of patients with sporadic papillary thyroid carcinomas : Correlation with more aggressive phenotype and decreased expression of iodide-metabolizing genes

✍ Gisele Oler; Janete M. Cerutti 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 166 KB 👁 1 views

## Abstract ## BACKGROUND: Although several studies undoubtedly demonstrated that __BRAF__ mutation is an important genetic event in the pathogenesis of papillary thyroid carcinoma (PTC), its prognostic significance and correlation with less differentiated states remains unclear. It has been sugge