We read with great interest the article by Martinot-Peignoux et al. 1 In this report from France, undetectable serum hepatitis C virus (HCV) RNA at 12 weeks (WΓΎ12) (409 patients) post-treatment follow-up was as relevant as undetectable serum HCV RNA at 24 weeks (WΓΎ24) (sustained virological response
Single nucleotide polymorphism upstream of interleukin 28B associated with phase 1 and phase 2 of early viral kinetics in patients infected with HCV genotype 1
β Scribed by Charles D. Howell; Alexis Gorden; Kathleen A. Ryan; Alexander J. Thompson; Chadi Ibrahim; Michael Fried; Nezam H. Afdhal; John G. McHutchison; Kevin V. Shianna; David B. Goldstein; Alan R. Shuldiner; Braxton D. Mitchell
- Book ID
- 116652638
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- English
- Weight
- 652 KB
- Volume
- 56
- Category
- Article
- ISSN
- 0168-8278
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## Abstract A study was carried out to determine whether early viral dynamics retain prediction of the outcome of peginterferon (PEGβIFN) and ribavirin combination therapy based on different genetic polymorphisms near the __IL28B__ gene, the strongest baseline predictor of response to this therapy.
We read with great interest the recent report by Li et al. 1 analyzing the correlation between the clusters of differentiation 24 (CD24) polymorphism and risk of chronic hepatitis B virus (HBV) infection. In their study, the CD24 P170 T allele (thymidine at position 170) was correlated with a strong