A method for typing single nucleotide polymorphisms (SNPs) by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOFMS) is described, in which a mass-tagged dideoxynucleoside triphosphate is employed in a primer extension reaction in place of an unmodified dideoxynuc
Single nucleotide polymorphism determination using primer extension and time-of-flight mass spectrometry
β Scribed by Jia Li; John M. Butler; Yuping Tan; Hua Lin; Stephanie Royer; Lynne Ohler; Thomas A. Shaler; Joanna M. Hunter; Daniel J. Pollart; Joseph A. Monforte; Christopher H. Becker
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 207 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0173-0835
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