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Single-molecule observations of neck linker conformational changes in the kinesin motor protein

โœ Scribed by Tomishige, Michio; Stuurman, Nico; Vale, Ronald D


Book ID
109966567
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
495 KB
Volume
13
Category
Article
ISSN
1545-9993

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The two-headed motor protein kinesin hydrolyzes ATP and moves on microtubule tracks towards the plus end. The motor develops speeds and forces of the order of hundreds of nanometers per second and piconewtons, respectively. Recently, the dependence of the velocity, the dissociation rate and the disp