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Single Molecule FRET Studies of Protein Conformational Landscapes: 3 Prototypic Examples for the Relation Between Conformational Dynamics and Function

✍ Scribed by Richert, Markus; Rodnin, Dymitro; Hengstenberg, Carola S.; Peulen, Thomas; Valeri, Alessandro; Rothwell, Paul J.; Millon, Pohl; Rodnina, Marina; Herrmann, Christian; Seidel, Claus A.M.

Book ID: 122181976
Publisher: Biophysical Society
Year: 2011
Tongue: English
Weight: 51 KB
Volume: 100
Category: Article
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2010.12.2782

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For the two steroid compounds 17aOH-progesterone and 21OH-progesterone, the activation energies of reorientations of the methyl groups have been determined. Their values together with results of the quantum chemical calculations permitted establishment of the sequence of the onset of the methyl grou