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Single-molecule DNA flexibility in the presence of base-pair mismatch

✍ Scribed by Schallhorn, Kathryn A.; Freedman, Katherine O.; Moore, Jessica M.; Lin, Jun; Ke, Pu Chun


Book ID
120462836
Publisher
American Institute of Physics
Year
2005
Tongue
English
Weight
449 KB
Volume
87
Category
Article
ISSN
0003-6951

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## Abstract An electrochemical approach for single base‐specific detection of label‐free target single‐strand DNA (ssDNA) was demonstrated. The approach was based on the high ligation selectivity of __Taq__ DNA ligase coupled with ferrocenated gold nanoparticle/streptavidin conjugate‐based voltamme