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Single infusion of zoledronate in Paget’s disease of bone: a placebo-controlled, dose-ranging study

✍ Scribed by H Buckler; W Fraser; D Hosking; W Ryan; M.J Maricic; F Singer; M Davie; I Fogelman; C.A Birbara; A.M Moses; K Lyles; P Selby; P Richardson; J Seaman; K Zelenakas; E Siris

Book ID: 117808856
Publisher: Elsevier Science
Year: 1999
Tongue: English
Weight: 77 KB
Volume: 24
Category: Article
ISSN: 8756-3282
DOI: 10.1016/s8756-3282(99)00071-x

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## Abstract Two trials have shown that a single 5‐mg infusion of zoledronic acid achieves much higher response rates in Paget disease of bone than risedronate. The duration of this effect is unknown. We have conducted an open follow‐up of responders from the two trials (152 originally treated with