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Single-Dose Pharmacokinetics of Sustained-Release Fampridine (Fampridine-SR) in Healthy Volunteers and Adults With Renal Impairment

✍ Scribed by Smith, William; Swan, Suzanne; Marbury, Thomas; Henney, Herbert


Book ID
118184068
Publisher
Sage Publications
Year
2010
Tongue
English
Weight
185 KB
Volume
50
Category
Article
ISSN
0091-2700

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The single-dose pharmacokinetics of nefazodone (NEF) and its metabolites hydroxynefazodone (HO-NEF) and m-chlorophenylpiperazine (mCPP) were examined in 12 healthy younger subjects < 55 years of age (YNG), 12 elderly subjects > 65 years of age (ELD), 12 patients with biopsy proven hepatic cirrhosis