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Single dose pharmacokinetics of (S)-atenolol administered orally as a single enantiomer formulation and as a racemic mixture (tenormin™)

✍ Scribed by Dr. William A. Clementi; Thomas Q. Garvey; G. Dennis Clifton; Randall A. McCoy; Steven Brandt; Sheldon Schwartz


Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
539 KB
Volume
6
Category
Article
ISSN
0899-0042

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## Abstract The pharmacokinetics of acebutolol have been studied in eight healthy male volunteers following the oral administration of acebutolol hydrochloride (‘Sectral’, May & Baker) as a single dose (400 mg), and during and after repeated oral dosing (400 mg, b.d. for 56 days). Following single