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Single-dose pharmacokinetics of quetiapine in subjects with renal or hepatic impairment

✍ Scribed by Per T Thyrum; Yw James Wong; Chiao Yeh

Book ID
117448744
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
835 KB
Volume
24
Category
Article
ISSN
0278-5846

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The single-dose pharmacokinetics of nefazodone (NEF) and its metabolites hydroxynefazodone (HO-NEF) and m-chlorophenylpiperazine (mCPP) were examined in 12 healthy younger subjects < 55 years of age (YNG), 12 elderly subjects > 65 years of age (ELD), 12 patients with biopsy proven hepatic cirrhosis