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Single-dose pharmacokinetics and safety of iptakalim hydrochloride in Chinese healthy volunteers

โœ Scribed by Yun Cai; Dong Chai; Fei Pei; Yi Fang; Rui Wang; Bei-bei Liang; Wen-yu Cui; Cun-gang Bao; Hai Wang


Book ID
118111624
Publisher
Pharmaceutical Press
Year
2011
Tongue
English
Weight
410 KB
Volume
64
Category
Article
ISSN
2042-7158

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The pharmacokinetics and tolerability of a new putative non-benzodiazepine type anxiolytic compound deramciclane was studied in two consecutive studies. An open dose-escalation design was used to study doses from 0.2 to 50 mg in 18 healthy male volunteers. In the second study doses from 50 to 150 mg