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Single channel properties of d-Leu2-gramicidin A side chain modulation of channel lifetime

✍ Scribed by Ronald J. Bradley; Kari U. Prasad; Dan W. Urry


Book ID
115725268
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
370 KB
Volume
649
Category
Article
ISSN
0005-2736

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Gramicidin A (gA) is prototypical peptide antibiotic and a model ion channel former. Configured in the solid-state NMR beta(6.5)-helix channel conformation, gA was subjected to 1-ns molecular dynamics (MD) gas phase simulations using the all-atom charmm22 force field to ascertain the conformational