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Single-channel analysis of two types of Na+currents in rat dorsal root ganglia

✍ Scribed by Haruhiko Motomura, Sadatoshi Fujikawa, Nobutada Tashiro, Yushi Ito…

Book ID
120903754
Publisher
Springer
Year
1995
Tongue
English
Weight
938 KB
Volume
431
Category
Article
ISSN
0031-6768

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✍ Nobukuni Ogata; Hideharu Tatebayashi 📂 Article 📅 1992 🏛 Springer 🌐 English ⚖ 884 KB

Whole-cell patch-clamp experiments were performed with neurons cultured from rat dorsal root ganglia (DRG). Two types of Na+ currents were identified on the basis of sensitivity to tetrodotoxin. One type was blocked by 0.1 nM tetrodotoxin, while the other type was insensitive to 10 microM tetrodotox